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SMILES: O=C1CC(=O)N(c2ccc(cc2)-c2cn(CCc3ccccc3)cn2)c2ccc3ccccc3c2N1

InChI Key: InChIKey=HIDZKOXZILPPML-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 366067   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2X purinoceptor 4


(Homo sapiens (Human))		BDBM366067
PNG
(US9873683, Example 73)
Show SMILES O=C1CC(=O)N(c2ccc(cc2)-c2cn(CCc3ccccc3)cn2)c2ccc3ccccc3c2N1
Show InChI InChI=1S/C30H24N4O2/c35-28-18-29(36)34(27-15-12-22-8-4-5-9-25(22)30(27)32-28)24-13-10-23(11-14-24)26-19-33(20-31-26)17-16-21-6-2-1-3-7-21/h1-15,19-20H,16-18H2,(H,32,35)
KEGG

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n/an/a 320n/an/an/an/an/an/a



Duquesne University



Assay Description
The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...

J Med Chem 51: 68-76 (2008)


BindingDB Entry DOI: 10.7270/Q2MW2KFS
More data for this
Ligand-Target Pair