BindingDB logo
myBDB logout

null

SMILES: Clc1ccc(Cn2cccc(C(=O)NCCCCc3c[nH]c4ncccc34)c2=O)cc1Cl

InChI Key: InChIKey=KWARGXAQPBUHEH-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 366341   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3-phosphoinositide-dependent protein kinase 1 [51-360]


(Homo sapiens (Human))		BDBM366341
PNG
(US9873693, Compound 269)
Show SMILES Clc1ccc(Cn2cccc(C(=O)NCCCCc3c[nH]c4ncccc34)c2=O)cc1Cl
Show InChI InChI=1S/C24H22Cl2N4O2/c25-20-9-8-16(13-21(20)26)15-30-12-4-7-19(24(30)32)23(31)28-10-2-1-5-17-14-29-22-18(17)6-3-11-27-22/h3-4,6-9,11-14H,1-2,5,10,15H2,(H,27,29)(H,28,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/an/an/a



Duquesne University



Assay Description
A PDK1 kinase assay was performed as follows. PDK1 (amino acids 51-360) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) ...

J Med Chem 51: 68-76 (2008)


BindingDB Entry DOI: 10.7270/Q2H41TRT
More data for this
Ligand-Target Pair