BDBM367611 N-[(1S)-2-[(4R,S)- 4-[2-(4-Amino-6- chloro-2-methyl- pyrimidin-5-yl)ethyl] azepan-1-yl]-1- methyl-2-oxo-ethyl] pyridine-4-carboxamide::US10227310, Example 37

SMILES: C[C@H](NC(=O)c1ccncc1)C(=O)N1CCCC(CCc2c(N)nc(C)nc2Cl)CC1

InChI Key: InChIKey=QMRFJSXKMZOFRR-LBAUFKAWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 367611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM367611 (N-[(1S)-2-[(4R,S)- 4-[2-(4-Amino-6- chloro-2-methy...) Show SMILES C[C@H](NC(=O)c1ccncc1)C(=O)N1CCCC(CCc2c(N)nc(C)nc2Cl)CC1 |r| Show InChI InChI=1S/C22H29ClN6O2/c1-14(26-21(30)17-7-10-25-11-8-17)22(31)29-12-3-4-16(9-13-29)5-6-18-19(23)27-15(2)28-20(18)24/h7-8,10-11,14,16H,3-6,9,12-13H2,1-2H3,(H,26,30)(H2,24,27,28)/t14-,16?/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	574	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Prepare test compounds in DMSO to make up a 0.2 mM stock solution. Serially dilute the stock solution in DMSO for ten concentrations with final compo...				J Med Chem 51: 1319-23 (2008) BindingDB Entry DOI: 10.7270/Q2KW5JBV
					More data for this Ligand-Target Pair