null

SMILES: O[C@@H]([C@@H](CN1CCC1)NC(=O)C1=NOCc2c1ccc1ccccc21)c1ccc(OC2CC2)c(Cl)c1

InChI Key: InChIKey=QBVMPVDBKBEAGJ-SHQCIBLASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367641   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ceramide glucosyltransferase (Homo sapiens (Human))	BDBM367641 (N-((1R,2R)-3-(azetidin-1-yl)-1-(3- chloro-4-cyclop...) Show SMILES O[C@@H]([C@@H](CN1CCC1)NC(=O)C1=NOCc2c1ccc1ccccc21)c1ccc(OC2CC2)c(Cl)c1 |r,t:12| Show InChI InChI=1S/C28H28ClN3O4/c29-23-14-18(7-11-25(23)36-19-8-9-19)27(33)24(15-32-12-3-13-32)30-28(34)26-21-10-6-17-4-1-2-5-20(17)22(21)16-35-31-26/h1-2,4-7,10-11,14,19,24,27,33H,3,8-9,12-13,15-16H2,(H,30,34)/t24-,27-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Protein concentration was determined using BCA assay kit. Sixty micrograms of MDCK cell lysate was incubated with various concentrations of a compoun...				US Patent US10759769 (2020)
					More data for this Ligand-Target Pair
Ceramide glucosyltransferase (Homo sapiens (Human))	BDBM367641 (N-((1R,2R)-3-(azetidin-1-yl)-1-(3- chloro-4-cyclop...) Show SMILES O[C@@H]([C@@H](CN1CCC1)NC(=O)C1=NOCc2c1ccc1ccccc21)c1ccc(OC2CC2)c(Cl)c1 |r,t:12| Show InChI InChI=1S/C28H28ClN3O4/c29-23-14-18(7-11-25(23)36-19-8-9-19)27(33)24(15-32-12-3-13-32)30-28(34)26-21-10-6-17-4-1-2-5-20(17)22(21)16-35-31-26/h1-2,4-7,10-11,14,19,24,27,33H,3,8-9,12-13,15-16H2,(H,30,34)/t24-,27-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...				J Med Chem 51: 1319-23 (2008) BindingDB Entry DOI: 10.7270/Q2G44SK0
					More data for this Ligand-Target Pair