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SMILES: COC(C)[C@@H](NC(=O)c1cc(ccc1F)C1CC1)C(=O)N1CCC2(CC1)N(C(=O)N(C)C2=O)c1ccc(OC)cc1

InChI Key: InChIKey=CQXUXMITFAPFPB-IXXGTQFESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369937   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2


(Homo sapiens (Human))		BDBM369937
PNG
(5-Cyclopropyl-2-fluoro-N-((2R,3R)-3-methoxy-1-(1-(...)
Show SMILES COC(C)[C@@H](NC(=O)c1cc(ccc1F)C1CC1)C(=O)N1CCC2(CC1)N(C(=O)N(C)C2=O)c1ccc(OC)cc1 |r|
Show InChI InChI=1S/C30H35FN4O6/c1-18(40-3)25(32-26(36)23-17-20(19-5-6-19)7-12-24(23)31)27(37)34-15-13-30(14-16-34)28(38)33(2)29(39)35(30)21-8-10-22(41-4)11-9-21/h7-12,17-19,25H,5-6,13-16H2,1-4H3,(H,32,36)/t18?,25-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/an/an/a



Merck Serono



Assay Description
The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...

J Med Chem 51: 2227-2243 (2008)


BindingDB Entry DOI: 10.7270/Q2QF8W5N
More data for this
Ligand-Target Pair