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SMILES: OC(=O)CCC(=O)OC(CC1c2ccccc2-c2cncn12)C1CCCCC1

InChI Key: InChIKey=KECJSORXVGLSAH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370509   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))		BDBM370509
PNG
(4-(1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5- yl...)
Show SMILES OC(=O)CCC(=O)OC(CC1c2ccccc2-c2cncn12)C1CCCCC1
Show InChI InChI=1S/C22H26N2O4/c25-21(26)10-11-22(27)28-20(15-6-2-1-3-7-15)12-18-16-8-4-5-9-17(16)19-13-23-14-24(18)19/h4-5,8-9,13-15,18,20H,1-3,6-7,10-12H2,(H,25,26)
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n/an/a 550n/an/an/an/an/an/a



Bayer HealthCare Pharmaceuticals Corporation



Assay Description
The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...

J Med Chem 50: 984-1000 (2007)


BindingDB Entry DOI: 10.7270/Q26H4KQM
More data for this
Ligand-Target Pair