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SMILES: [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cc1)C2)Oc1ccc(cc1)C#N

InChI Key: InChIKey=BFVMPXRFQIJVEL-UEDVBVCCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370702   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))		BDBM370702
PNG
(US10239835, Example 00254)
Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cc1)C2)Oc1ccc(cc1)C#N |r,w:10.11|
Show InChI InChI=1S/C22H24N2O3/c23-11-15-1-7-20(8-2-15)27-21-9-17-12-24(13-18(17)10-21)14-22(26)16-3-5-19(25)6-4-16/h1-8,17-18,21-22,25-26H,9-10,12-14H2/t17-,18+,21+,22?
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 47.4n/an/an/an/an/an/a



Bayer HealthCare Pharmaceuticals Corporation



Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...

J Med Chem 50: 984-1000 (2007)


BindingDB Entry DOI: 10.7270/Q2F19207
More data for this
Ligand-Target Pair