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SMILES: [H][C@@]12C[C@@H](C[C@]1([H])CN(CC(=O)c1ccc(O)cc1)C2)Oc1ccc(OC)cc1

InChI Key: InChIKey=AHVZMBZEGLLKGP-UPHUGPLXSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370718   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))		BDBM370718
PNG
(US10239835, Example 00270)
Show SMILES [H][C@@]12C[C@@H](C[C@]1([H])CN(CC(=O)c1ccc(O)cc1)C2)Oc1ccc(OC)cc1 |r|
Show InChI InChI=1S/C22H25NO4/c1-26-19-6-8-20(9-7-19)27-21-10-16-12-23(13-17(16)11-21)14-22(25)15-2-4-18(24)5-3-15/h2-9,16-17,21,24H,10-14H2,1H3/t16-,17+,21-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 57.3n/an/an/an/an/an/a



Bayer HealthCare Pharmaceuticals Corporation



Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...

J Med Chem 50: 984-1000 (2007)


BindingDB Entry DOI: 10.7270/Q2F19207
More data for this
Ligand-Target Pair