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SMILES: [H][C@@]12C[C@H](C[C@]1([H])CN(CC(=O)c1ccc(O)cc1)C2)Oc1ccc(F)nc1

InChI Key: InChIKey=NBMFDLJISBGKDP-HWWDLCQESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370758   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))		BDBM370758
PNG
(US10239835, Example 00310)
Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(=O)c1ccc(O)cc1)C2)Oc1ccc(F)nc1 |r|
Show InChI InChI=1S/C20H21FN2O3/c21-20-6-5-17(9-22-20)26-18-7-14-10-23(11-15(14)8-18)12-19(25)13-1-3-16(24)4-2-13/h1-6,9,14-15,18,24H,7-8,10-12H2/t14-,15+,18+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 55.2n/an/an/an/an/an/a



Bayer HealthCare Pharmaceuticals Corporation



Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...

J Med Chem 50: 984-1000 (2007)


BindingDB Entry DOI: 10.7270/Q2F19207
More data for this
Ligand-Target Pair