BDBM370809 US10239835, Example 00361

SMILES: [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cc1)C2)Sc1ccc(F)cc1

InChI Key: InChIKey=OPNBOJOJFVMDER-SDSGSWQQSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370809   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370809 (US10239835, Example 00361) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cc1)C2)Sc1ccc(F)cc1 |r,w:10.11| Show InChI InChI=1S/C21H24FNO2S/c22-17-3-7-19(8-4-17)26-20-9-15-11-23(12-16(15)10-20)13-21(25)14-1-5-18(24)6-2-14/h1-8,15-16,20-21,24-25H,9-13H2/t15-,16+,20+,21?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.2	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair