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SMILES: [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Sc1ccccc1F

InChI Key: InChIKey=ZYFOTZUIRJMEAQ-WQULZKCCSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370812   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))		BDBM370812
PNG
(US10239835, Example 00363)
Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Sc1ccccc1F |r,w:10.11|
Show InChI InChI=1S/C20H23FN2O2S/c21-17-3-1-2-4-20(17)26-16-7-13-10-23(11-14(13)8-16)12-19(25)18-6-5-15(24)9-22-18/h1-6,9,13-14,16,19,24-25H,7-8,10-12H2/t13-,14+,16+,19?
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 20.6n/an/an/an/an/an/a



Bayer HealthCare Pharmaceuticals Corporation



Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...

J Med Chem 50: 984-1000 (2007)


BindingDB Entry DOI: 10.7270/Q2F19207
More data for this
Ligand-Target Pair