BDBM371008 US10239843, Example 115

SMILES: Cc1noc(C)c1Cn1c(=O)n(C)c2ccc(cc2c1=O)S(=O)(=O)NC1(C)CC1

InChI Key: InChIKey=HABIRWSCTVMHSY-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 371008   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
poly(ADP-ribose) glycohydrolase (PARG) (Homo sapiens (Human))	BDBM371008 (US10239843, Example 115) Show SMILES Cc1noc(C)c1Cn1c(=O)n(C)c2ccc(cc2c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C19H22N4O5S/c1-11-15(12(2)28-20-11)10-23-17(24)14-9-13(5-6-16(14)22(4)18(23)25)29(26,27)21-19(3)7-8-19/h5-6,9,21H,7-8,10H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	620	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assay				J Med Chem 61: 10767-10792 (2018) Article DOI: 10.1021/acs.jmedchem.8b01407 BindingDB Entry DOI: 10.7270/Q2TM7DTN
					More data for this Ligand-Target Pair
poly(ADP-ribose) glycohydrolase (PARG) (Homo sapiens (Human))	BDBM371008 (US10239843, Example 115) Show SMILES Cc1noc(C)c1Cn1c(=O)n(C)c2ccc(cc2c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C19H22N4O5S/c1-11-15(12(2)28-20-11)10-23-17(24)14-9-13(5-6-16(14)22(4)18(23)25)29(26,27)21-19(3)7-8-19/h5-6,9,21H,7-8,10H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	616	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanita					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				J Med Chem 51: 1058-62 (2008) BindingDB Entry DOI: 10.7270/Q21R6SSM
					More data for this Ligand-Target Pair