null

SMILES: CC1(CC1)NS(=O)(=O)c1ccc2ccnc(Cl)c2c1

InChI Key: InChIKey=HJSXARKGWKUBAJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 371376   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM371376 (1-Chloro-N-(1-methylcyclopropyl)isoquinoline-7-sul...) Show SMILES CC1(CC1)NS(=O)(=O)c1ccc2ccnc(Cl)c2c1 Show InChI InChI=1S/C13H13ClN2O2S/c1-13(5-6-13)16-19(17,18)10-3-2-9-4-7-15-12(14)11(9)8-10/h2-4,7-8,16H,5-6H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanita					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				J Med Chem 51: 1058-62 (2008) BindingDB Entry DOI: 10.7270/Q21R6SSM
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM371376 (1-Chloro-N-(1-methylcyclopropyl)isoquinoline-7-sul...) Show SMILES CC1(CC1)NS(=O)(=O)c1ccc2ccnc(Cl)c2c1 Show InChI InChI=1S/C13H13ClN2O2S/c1-13(5-6-13)16-19(17,18)10-3-2-9-4-7-15-12(14)11(9)8-10/h2-4,7-8,16H,5-6H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanita					Assay Description PARP1 In vitro selectivity assays were conducted as a 10 ul reaction volume in a NUNC Maxisorp 384-well assay plate pre-coated in-house with Histones...				J Med Chem 51: 1058-62 (2008) BindingDB Entry DOI: 10.7270/Q21R6SSM
					More data for this Ligand-Target Pair
ADP-ribosylhydrolase ARH3 (Homo sapiens (Human))	BDBM371376 (1-Chloro-N-(1-methylcyclopropyl)isoquinoline-7-sul...) Show SMILES CC1(CC1)NS(=O)(=O)c1ccc2ccnc(Cl)c2c1 Show InChI InChI=1S/C13H13ClN2O2S/c1-13(5-6-13)16-19(17,18)10-3-2-9-4-7-15-12(14)11(9)8-10/h2-4,7-8,16H,5-6H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanita					Assay Description ARH3 In vitro selectivity assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length ARH3 (Enzo Life S...				J Med Chem 51: 1058-62 (2008) BindingDB Entry DOI: 10.7270/Q21R6SSM
					More data for this Ligand-Target Pair