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SMILES: CCn1ncc(NC2CCCCN(C)C2)c(Cl)c1=O

InChI Key: InChIKey=QRSGFCIBFDURJI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371535   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371535
PNG
(4-chloro-2-ethyl-5-((1-methylazepan-3-yl)amino)pyr...)
Show SMILES CCn1ncc(NC2CCCCN(C)C2)c(Cl)c1=O
Show InChI InChI=1S/C13H21ClN4O/c1-3-18-13(19)12(14)11(8-15-18)16-10-6-4-5-7-17(2)9-10/h8,10,16H,3-7,9H2,1-2H3
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PC cid
PC sid
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US Patent
n/an/a 407n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair