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SMILES: CN(C)c1ccc(CN2CCCC(C2)Nc2cnn(C)c(=O)c2Cl)cc1

InChI Key: InChIKey=GHHAWASMXAKDGB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371563   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371563
PNG
(4-chloro-5-[[1-[(4-dimethylaminophenyl)methyl]-3-p...)
Show SMILES CN(C)c1ccc(CN2CCCC(C2)Nc2cnn(C)c(=O)c2Cl)cc1
Show InChI InChI=1S/C19H26ClN5O/c1-23(2)16-8-6-14(7-9-16)12-25-10-4-5-15(13-25)22-17-11-21-24(3)19(26)18(17)20/h6-9,11,15,22H,4-5,10,12-13H2,1-3H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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PC cid
PC sid
UniChem
US Patent
n/an/a 310n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair