BDBM372016 US10239870, Example 276

SMILES: Cn1c(SCCCN2CC[C@]3(C[C@@H]3c3ccc(cc3)C(F)(F)F)C2)nnc1-c1ccc(cc1)-n1cnnc1

InChI Key: InChIKey=YGYAGUWNTSRVJU-BVAGGSTKSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372016   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM372016 (US10239870, Example 276) Show SMILES Cn1c(SCCCN2CC[C@]3(C[C@@H]3c3ccc(cc3)C(F)(F)F)C2)nnc1-c1ccc(cc1)-n1cnnc1 |r| Show InChI InChI=1S/C27H28F3N7S/c1-35-24(20-5-9-22(10-6-20)37-17-31-32-18-37)33-34-25(35)38-14-2-12-36-13-11-26(16-36)15-23(26)19-3-7-21(8-4-19)27(28,29)30/h3-10,17-18,23H,2,11-16H2,1H3/t23-,26+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.363	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description [125I]-7OH-PIPAT Binding Assay at rat native D3 receptor on membranes from rat ventral striatum. Homogenates from frozen rat brain ventral striatum (...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2HT2RNX
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM372016 (US10239870, Example 276) Show SMILES Cn1c(SCCCN2CC[C@]3(C[C@@H]3c3ccc(cc3)C(F)(F)F)C2)nnc1-c1ccc(cc1)-n1cnnc1 |r| Show InChI InChI=1S/C27H28F3N7S/c1-35-24(20-5-9-22(10-6-20)37-17-31-32-18-37)33-34-25(35)38-14-2-12-36-13-11-26(16-36)15-23(26)19-3-7-21(8-4-19)27(28,29)30/h3-10,17-18,23H,2,11-16H2,1H3/t23-,26+/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	166	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to Gα16 protein (CHO-Gα16-hD2L) were re-suspended ...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2HT2RNX
					More data for this Ligand-Target Pair