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SMILES: CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccnc2cc(ccc12)C#N

InChI Key: InChIKey=CBNLXZBTQVYRAC-QHCPKHFHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 373608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM373608 ((S)-4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-(trif...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccnc2cc(ccc12)C#N |r| Show InChI InChI=1S/C24H24F3N3O/c1-15(2)12-23(3,29)14-31-22-7-5-17(11-20(22)24(25,26)27)18-8-9-30-21-10-16(13-28)4-6-19(18)21/h4-11,15H,12,14,29H2,1-3H3/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.660	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 Cl prepared from 15 μl additions of enzyme and substrates (...				US Patent US10723734 (2020)
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM373608 ((S)-4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-(trif...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccnc2cc(ccc12)C#N |r| Show InChI InChI=1S/C24H24F3N3O/c1-15(2)12-23(3,29)14-31-22-7-5-17(11-20(22)24(25,26)27)18-8-9-30-21-10-16(13-28)4-6-19(18)21/h4-11,15H,12,14,29H2,1-3H3/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.660	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q2930WGG
					More data for this Ligand-Target Pair