BDBM374872 US10251893, Cpd 76

SMILES: Cc1cc(CC(=O)Nc2ccc(cn2)-c2ccccn2)ccc1-c1ccnnc1

InChI Key: InChIKey=YSVYQCLGPIVOTJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374872   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Wnt-3a (Homo sapiens (Human))	BDBM374872 (US10251893, Cpd 76) Show SMILES Cc1cc(CC(=O)Nc2ccc(cn2)-c2ccccn2)ccc1-c1ccnnc1 Show InChI InChI=1S/C23H19N5O/c1-16-12-17(5-7-20(16)18-9-11-26-27-15-18)13-23(29)28-22-8-6-19(14-25-22)21-4-2-3-10-24-21/h2-12,14-15H,13H2,1H3,(H,25,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Research Hospital					Assay Description Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...				J Med Chem 50: 5727-34 (2007) BindingDB Entry DOI: 10.7270/Q2GM89KJ
					More data for this Ligand-Target Pair