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SMILES: Cc1cc(ccn1)-c1ccc(CC(=O)Nc2ccc(nn2)-c2ccccc2)cn1

InChI Key: InChIKey=VSSSTCHRPRTQJF-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374902   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein Wnt-3a


(Homo sapiens (Human))		BDBM374902
PNG
(US10251893, Cpd 110)
Show SMILES Cc1cc(ccn1)-c1ccc(CC(=O)Nc2ccc(nn2)-c2ccccc2)cn1
Show InChI InChI=1S/C23H19N5O/c1-16-13-19(11-12-24-16)20-8-7-17(15-25-20)14-23(29)26-22-10-9-21(27-28-22)18-5-3-2-4-6-18/h2-13,15H,14H2,1H3,(H,26,28,29)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 0.0800n/an/an/an/an/an/a



St. Jude Research Hospital



Assay Description
Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...

J Med Chem 50: 5727-34 (2007)


BindingDB Entry DOI: 10.7270/Q2GM89KJ
More data for this
Ligand-Target Pair