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SMILES: FC(F)(F)c1cc(CC(=O)Nc2ccc(cn2)-c2cnccn2)ccc1-c1ccnnc1

InChI Key: InChIKey=IXUONQDRNSJHDC-UHFFFAOYSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374910   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein Wnt-3a


(Homo sapiens (Human))		BDBM374910
PNG
(N-(5-(pyrazin-2-yl)pyridin-2-yl)-2-(4-(pyridazin-4...)
Show SMILES FC(F)(F)c1cc(CC(=O)Nc2ccc(cn2)-c2cnccn2)ccc1-c1ccnnc1
Show InChI InChI=1S/C22H15F3N6O/c23-22(24,25)18-9-14(1-3-17(18)15-5-6-29-30-12-15)10-21(32)31-20-4-2-16(11-28-20)19-13-26-7-8-27-19/h1-9,11-13H,10H2,(H,28,31,32)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 0.100n/an/an/an/an/an/a



St. Jude Research Hospital



Assay Description
Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...

J Med Chem 50: 5727-34 (2007)


BindingDB Entry DOI: 10.7270/Q2GM89KJ
More data for this
Ligand-Target Pair