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SMILES: Cc1cc(ccn1)-c1ccc(CC(=O)Nc2ccc(cn2)N2CCN(CC2)C(=O)OC(C)(C)C)cc1

InChI Key: InChIKey=LJXAERRBWAZHPF-UHFFFAOYSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374917   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein Wnt-3a


(Homo sapiens (Human))		BDBM374917
PNG
(US10251893, Cpd 125 | tert-butyl 4-(6-(2-(4-(2-met...)
Show SMILES Cc1cc(ccn1)-c1ccc(CC(=O)Nc2ccc(cn2)N2CCN(CC2)C(=O)OC(C)(C)C)cc1
Show InChI InChI=1S/C28H33N5O3/c1-20-17-23(11-12-29-20)22-7-5-21(6-8-22)18-26(34)31-25-10-9-24(19-30-25)32-13-15-33(16-14-32)27(35)36-28(2,3)4/h5-12,17,19H,13-16,18H2,1-4H3,(H,30,31,34)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 0.200n/an/an/an/an/an/a



St. Jude Research Hospital



Assay Description
Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...

J Med Chem 50: 5727-34 (2007)


BindingDB Entry DOI: 10.7270/Q2GM89KJ
More data for this
Ligand-Target Pair