BDBM376936 US9920047, 66

SMILES: Cc1sc(cc1C(=O)NC1CCC(F)(F)CC1)[C@@H]1C[C@H]1NCC1CCOCC1

InChI Key: InChIKey=WNXSJWZABTXFHH-QZTJIDSGSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 376936   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM376936 (US9920047, 66) Show SMILES Cc1sc(cc1C(=O)NC1CCC(F)(F)CC1)[C@@H]1C[C@H]1NCC1CCOCC1 Show InChI InChI=1S/C21H30F2N2O2S/c1-13-16(20(26)25-15-2-6-21(22,23)7-3-15)11-19(28-13)17-10-18(17)24-12-14-4-8-27-9-5-14/h11,14-15,17-18,24H,2-10,12H2,1H3,(H,25,26)/t17-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q2R213PQ
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM376936 (US9920047, 66) Show SMILES Cc1sc(cc1C(=O)NC1CCC(F)(F)CC1)[C@@H]1C[C@H]1NCC1CCOCC1 Show InChI InChI=1S/C21H30F2N2O2S/c1-13-16(20(26)25-15-2-6-21(22,23)7-3-15)11-19(28-13)17-10-18(17)24-12-14-4-8-27-9-5-14/h11,14-15,17-18,24H,2-10,12H2,1H3,(H,25,26)/t17-,18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol, 10% DMSO) containing MAO-B enzyme (Sigma-Aldr...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q2R213PQ
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM376936 (US9920047, 66) Show SMILES Cc1sc(cc1C(=O)NC1CCC(F)(F)CC1)[C@@H]1C[C@H]1NCC1CCOCC1 Show InChI InChI=1S/C21H30F2N2O2S/c1-13-16(20(26)25-15-2-6-21(22,23)7-3-15)11-19(28-13)17-10-18(17)24-12-14-4-8-27-9-5-14/h11,14-15,17-18,24H,2-10,12H2,1H3,(H,25,26)/t17-,18-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q2R213PQ
					More data for this Ligand-Target Pair