null

SMILES: O[C@H]([C@@H](O)C(=O)NCCOCCOCCNS(=O)(=O)c1ccc(O[C@@H]2[C@H](Cc3ccccc23)N2CCCCC2)cc1)C(=O)NCCOCCOCCNS(=O)(=O)c1ccc(O[C@@H]2[C@H](Cc3ccccc23)N2CCCCC2)cc1

InChI Key: InChIKey=HDGZWIAEZJRQLN-OHAFZUPBSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 381741   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 3 (Homo sapiens (Human))	BDBM381741 (US10272079, Compound 98) Show SMILES O[C@H]([C@@H](O)C(=O)NCCOCCOCCNS(=O)(=O)c1ccc(O[C@@H]2[C@H](Cc3ccccc23)N2CCCCC2)cc1)C(=O)NCCOCCOCCNS(=O)(=O)c1ccc(O[C@@H]2[C@H](Cc3ccccc23)N2CCCCC2)cc1 |r| Show InChI InChI=1S/C56H76N6O14S2/c63-51(55(65)57-23-31-71-35-37-73-33-25-59-77(67,68)45-19-15-43(16-20-45)75-53-47-13-5-3-11-41(47)39-49(53)61-27-7-1-8-28-61)52(64)56(66)58-24-32-72-36-38-74-34-26-60-78(69,70)46-21-17-44(18-22-46)76-54-48-14-6-4-12-42(48)40-50(54)62-29-9-2-10-30-62/h3-6,11-22,49-54,59-60,63-64H,1-2,7-10,23-40H2,(H,57,65)(H,58,66)/t49-,50-,51+,52+,53-,54-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.94	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q2251MHH
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Rattus norvegicus)	BDBM381741 (US10272079, Compound 98) Show SMILES O[C@H]([C@@H](O)C(=O)NCCOCCOCCNS(=O)(=O)c1ccc(O[C@@H]2[C@H](Cc3ccccc23)N2CCCCC2)cc1)C(=O)NCCOCCOCCNS(=O)(=O)c1ccc(O[C@@H]2[C@H](Cc3ccccc23)N2CCCCC2)cc1 |r| Show InChI InChI=1S/C56H76N6O14S2/c63-51(55(65)57-23-31-71-35-37-73-33-25-59-77(67,68)45-19-15-43(16-20-45)75-53-47-13-5-3-11-41(47)39-49(53)61-27-7-1-8-28-61)52(64)56(66)58-24-32-72-36-38-74-34-26-60-78(69,70)46-21-17-44(18-22-46)76-54-48-14-6-4-12-42(48)40-50(54)62-29-9-2-10-30-62/h3-6,11-22,49-54,59-60,63-64H,1-2,7-10,23-40H2,(H,57,65)(H,58,66)/t49-,50-,51+,52+,53-,54-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.98	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q2251MHH
					More data for this Ligand-Target Pair