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BDBM382126 4-(4-((4'-(1-cyanocyclopropyl)-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methoxy)phenyl) butanoic Acid::US10273230, Compound of Example 1

SMILES: OC(=O)CCCc1ccc(OCC2=C(CCCC2)c2ccc(cc2)C2(CC2)C#N)cc1

InChI Key: InChIKey=JOWQJLSUUMGECS-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 382126   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
G-protein coupled receptor 120


(Homo sapiens (Human))		BDBM382126
PNG
(4-(4-((4'-(1-cyanocyclopropyl)-3,4,5,6-tetrahydro-...)
Show SMILES OC(=O)CCCc1ccc(OCC2=C(CCCC2)c2ccc(cc2)C2(CC2)C#N)cc1 |t:12|
Show InChI InChI=1S/C27H29NO3/c28-19-27(16-17-27)23-12-10-21(11-13-23)25-6-2-1-5-22(25)18-31-24-14-8-20(9-15-24)4-3-7-26(29)30/h8-15H,1-7,16-18H2,(H,29,30)
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KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2.75E+3n/an/an/an/a



IRBM/Merck



Assay Description
Beta (β) arrestin 2 Interaction Assay (BRET assay) was performed using CHO-K1 cells stably expressing the GPR120 receptor using β-galactosi...

Bioorg Med Chem Lett 18: 3456-61 (2008)


BindingDB Entry DOI: 10.7270/Q2154KBP
More data for this
Ligand-Target Pair