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BDBM382127 4-(4-((2-(4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)cyclohex-1-en-1-yl)methoxy)phenyl) butanoic Acid::US10273230, Compound of Example 4

SMILES: OC(=O)CCCc1ccc(OCC2=C(CCCC2)c2nc3CCCCc3s2)cc1

InChI Key: InChIKey=AIOVROYYYWTOIL-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 382127   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
G-protein coupled receptor 120


(Homo sapiens (Human))		BDBM382127
PNG
(4-(4-((2-(4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)c...)
Show SMILES OC(=O)CCCc1ccc(OCC2=C(CCCC2)c2nc3CCCCc3s2)cc1 |t:12|
Show InChI InChI=1S/C24H29NO3S/c26-23(27)11-5-6-17-12-14-19(15-13-17)28-16-18-7-1-2-8-20(18)24-25-21-9-3-4-10-22(21)29-24/h12-15H,1-11,16H2,(H,26,27)
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2.75E+3n/an/an/an/a



IRBM/Merck



Assay Description
Beta (β) arrestin 2 Interaction Assay (BRET assay) was performed using CHO-K1 cells stably expressing the GPR120 receptor using β-galactosi...

Bioorg Med Chem Lett 18: 3456-61 (2008)


BindingDB Entry DOI: 10.7270/Q2154KBP
More data for this
Ligand-Target Pair