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SMILES: NC\C(COc1cnc(nc1)N1CC[C@H](O)C1)=C/F

InChI Key: InChIKey=PGWHLRYXOSBDBE-RZCNENHTSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 385389   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM385389 ((3 S)-1-[5-[(E)-2-(Aminomethyl)-3-fluoro-allyloxy]...) Show SMILES NC\C(COc1cnc(nc1)N1CC[C@H](O)C1)=C/F |r| Show InChI InChI=1S/C12H17FN4O2/c13-3-9(4-14)8-19-11-5-15-12(16-6-11)17-2-1-10(18)7-17/h3,5-6,10,18H,1-2,4,7-8,14H2/b9-3+/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford					Assay Description Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo™ assay kit from Promega (V1402). Test compounds (w...				J Med Chem 51: 7057-60 (2008) BindingDB Entry DOI: 10.7270/Q2C82CM5
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM385389 ((3 S)-1-[5-[(E)-2-(Aminomethyl)-3-fluoro-allyloxy]...) Show SMILES NC\C(COc1cnc(nc1)N1CC[C@H](O)C1)=C/F |r| Show InChI InChI=1S/C12H17FN4O2/c13-3-9(4-14)8-19-11-5-15-12(16-6-11)17-2-1-10(18)7-17/h3,5-6,10,18H,1-2,4,7-8,14H2/b9-3+/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
ELI LILLY AND COMPANY US Patent					Assay Description Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo™ assay kit from Promega (V1402). Test compounds (w...				US Patent US10793552 (2020)
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM385389 ((3 S)-1-[5-[(E)-2-(Aminomethyl)-3-fluoro-allyloxy]...) Show SMILES NC\C(COc1cnc(nc1)N1CC[C@H](O)C1)=C/F |r| Show InChI InChI=1S/C12H17FN4O2/c13-3-9(4-14)8-19-11-5-15-12(16-6-11)17-2-1-10(18)7-17/h3,5-6,10,18H,1-2,4,7-8,14H2/b9-3+/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo™ assay kit from Promega (V1402). Test compounds (w...				US Patent US10464928 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K1J
					More data for this Ligand-Target Pair