BDBM385766 N-[5-(4-cyano-3- fluorophenyl)- [1,2,4]triazolo[1,5- a]pyridin-5-yl]-2- cyclopropyl- acetamide::US10287286, Example 169

SMILES: Fc1cc(ccc1C#N)-c1cc(NC(=O)CC2CC2)cc2ncnn12

InChI Key: InChIKey=UHZBVANUVKROCY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 385766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 2 (Homo sapiens (Human))	BDBM385766 (N-[5-(4-cyano-3- fluorophenyl)- [1,2,4]triazolo[1,...) Show SMILES Fc1cc(ccc1C#N)-c1cc(NC(=O)CC2CC2)cc2ncnn12 Show InChI InChI=1S/C18H14FN5O/c19-15-6-12(3-4-13(15)9-20)16-7-14(8-17-21-10-22-24(16)17)23-18(25)5-11-1-2-11/h3-4,6-8,10-11H,1-2,5H2,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze					Assay Description The IC50 values for the PHD1 enzyme (residues 1-407) were determined by mixing increasing amounts of a compound of the invention with a fixed amount ...				Bioorg Med Chem 16: 7424-8 (2008) BindingDB Entry DOI: 10.7270/Q2QJ7KMD
					More data for this Ligand-Target Pair