BDBM387266 N-(5′- (4-Ethyl-5-oxo-4,5- dihydro-1,3,4- oxadiazol-2-yl)-2′- methyl-[1,1′- biphenyl]-4-yl)-2,6- difluorobenzamide::US10292981, Example 34

SMILES: CCn1nc(oc1=O)-c1ccc(C)c(c1)-c1ccc(NC(=O)c2c(F)cccc2F)cc1

InChI Key: InChIKey=OWPMRXOYWPQBNY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387266   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 (Homo sapiens (Human))	BDBM387266 (N-(5′- (4-Ethyl-5-oxo-4,5- dihydro-1,3,4- ...) Show SMILES CCn1nc(oc1=O)-c1ccc(C)c(c1)-c1ccc(NC(=O)c2c(F)cccc2F)cc1 Show InChI InChI=1S/C24H19F2N3O3/c1-3-29-24(31)32-23(28-29)16-8-7-14(2)18(13-16)15-9-11-17(12-10-15)27-22(30)21-19(25)5-4-6-20(21)26/h4-13H,3H2,1-2H3,(H,27,30)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...				Bioorg Med Chem Lett 18: 1958-62 (2008) BindingDB Entry DOI: 10.7270/Q2D50Q8B
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