BDBM387270 2,6- Difluoro-N-(5-(2- methyl-5-(4- methyl-5-oxo-4,5- dihydro-1,3,4- oxadiazol-2- yl)phenyl)pyrazin- 2-yl)benzamide::US10292981, Example 87

SMILES: Cc1ccc(cc1-c1cnc(NC(=O)c2c(F)cccc2F)cn1)-c1nn(C)c(=O)o1

InChI Key: InChIKey=NQLUEONWNDPITM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 (Homo sapiens (Human))	BDBM387270 (2,6- Difluoro-N-(5-(2- methyl-5-(4- methyl-5-oxo-4...) Show SMILES Cc1ccc(cc1-c1cnc(NC(=O)c2c(F)cccc2F)cn1)-c1nn(C)c(=O)o1 Show InChI InChI=1S/C21H15F2N5O3/c1-11-6-7-12(20-27-28(2)21(30)31-20)8-13(11)16-9-25-17(10-24-16)26-19(29)18-14(22)4-3-5-15(18)23/h3-10H,1-2H3,(H,25,26,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...				Bioorg Med Chem Lett 18: 1958-62 (2008) BindingDB Entry DOI: 10.7270/Q2D50Q8B
					More data for this Ligand-Target Pair