BDBM38843 (3-methylcinnolin-5-yl)amine::3-methyl-5-cinnolinamine::3-methylcinnolin-5-amine::MLS000105193::SMR000055122::cid_5310645
SMILES: Cc1cc2c(N)cccc2nn1
InChI Key: InChIKey=HOJQDQQMHMVETF-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide (Homo sapiens (Human)) | BDBM38843![]() ((3-methylcinnolin-5-yl)amine | 3-methyl-5-cinnolin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | PCBioAssay | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay | Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN MLSCN Grant: 1 X01MH78953-01 The 14-3-3 pr... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2V986FT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity phosphatase Cdc25B (Homo sapiens (Human)) | BDBM38843![]() ((3-methylcinnolin-5-yl)amine | 3-methyl-5-cinnolin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | PCBioAssay | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay | Assay Description The Cdc25B Phosphatase HTS dose response confirmation has been developed to confirm actives identified in the Cdc25B HTS AID 368, screened at the Uni... | PubChem Bioassay (2006) BindingDB Entry DOI: 10.7270/Q2BG2MCP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA recombination protein RecA (Mycobacterium tuberculosis H37Rv) | BDBM38843![]() ((3-methylcinnolin-5-yl)amine | 3-methyl-5-cinnolin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | PCBioAssay | n/a | n/a | n/a | n/a | 9.91E+4 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2FN14NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA recombination protein RecA (Mycobacterium tuberculosis H37Rv) | BDBM38843![]() ((3-methylcinnolin-5-yl)amine | 3-methyl-5-cinnolin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | PCBioAssay | n/a | n/a | n/a | n/a | 5.46E+4 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2DR2SX9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human)) | BDBM38843![]() ((3-methylcinnolin-5-yl)amine | 3-methyl-5-cinnolin...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 2.72E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS... | PubChem Bioassay (2014) BindingDB Entry DOI: 10.7270/Q2WS8RXV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SUMO/sentrin specific peptidase family member 8 (Homo sapiens (Human)) | BDBM38843![]() ((3-methylcinnolin-5-yl)amine | 3-methyl-5-cinnolin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 2.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2P849HJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chain E, Fragment Double-D From Human Fibrin (Homo sapiens (Human)) | BDBM38843![]() ((3-methylcinnolin-5-yl)amine | 3-methyl-5-cinnolin...) | PDB MMDB Reactome pathway B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 8.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: Harvard Medical School/Massachuset... | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2VX0F59 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chain E, Fragment Double-D From Human Fibrin (Homo sapiens (Human)) | BDBM38843![]() ((3-methylcinnolin-5-yl)amine | 3-methyl-5-cinnolin...) | PDB MMDB Reactome pathway B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 8.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: Harvard Medical School/Massachuset... | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2R49PFB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SUMO/sentrin specific peptidase family member 8 (Homo sapiens (Human)) | BDBM38843![]() ((3-methylcinnolin-5-yl)amine | 3-methyl-5-cinnolin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 2.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2JM2870 | ||||||||||||
More data for this Ligand-Target Pair |