BDBM389045 USRE46792, 63

SMILES: COc1ccc(cc1OCC(C)C)-c1nc(CNC(=O)c2ccccc2OC)co1

InChI Key: InChIKey=MYPVQCDKTKOVLP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 389045   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM389045 (USRE46792, 63) Show SMILES COc1ccc(cc1OCC(C)C)-c1nc(CNC(=O)c2ccccc2OC)co1 Show InChI InChI=1S/C23H26N2O5/c1-15(2)13-29-21-11-16(9-10-20(21)28-4)23-25-17(14-30-23)12-24-22(26)18-7-5-6-8-19(18)27-3/h5-11,14-15H,12-13H2,1-4H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere					Assay Description Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...				J Med Chem 52: 646-54 (2009) BindingDB Entry DOI: 10.7270/Q2DZ0BNN
					More data for this Ligand-Target Pair