BDBM389073 USRE46792, 170

SMILES: COc1ccc(cc1OCC1CC1)-c1nc(CCC(=O)c2ccccc2OC)co1

InChI Key: InChIKey=OPOBOJVOXNWQEA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 389073   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM389073 (USRE46792, 170) Show SMILES COc1ccc(cc1OCC1CC1)-c1nc(CCC(=O)c2ccccc2OC)co1 Show InChI InChI=1S/C24H25NO5/c1-27-21-6-4-3-5-19(21)20(26)11-10-18-15-30-24(25-18)17-9-12-22(28-2)23(13-17)29-14-16-7-8-16/h3-6,9,12-13,15-16H,7-8,10-11,14H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere					Assay Description Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...				J Med Chem 52: 646-54 (2009) BindingDB Entry DOI: 10.7270/Q2DZ0BNN
					More data for this Ligand-Target Pair