BDBM390773 US9957263, Example 35

SMILES: Cn1cc(-c2cc(ccc2Oc2cccc(c2)C(=O)NCCN2CCCC2)S(C)(=O)=O)c2cc[nH]c2c1=O

InChI Key: InChIKey=ONSQEGDHBDISIX-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM390773 (US9957263, Example 35) Show SMILES Cn1cc(-c2cc(ccc2Oc2cccc(c2)C(=O)NCCN2CCCC2)S(C)(=O)=O)c2cc[nH]c2c1=O Show InChI InChI=1S/C28H30N4O5S/c1-31-18-24(22-10-11-29-26(22)28(31)34)23-17-21(38(2,35)36)8-9-25(23)37-20-7-5-6-19(16-20)27(33)30-12-15-32-13-3-4-14-32/h5-11,16-18,29H,3-4,12-15H2,1-2H3,(H,30,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...				Bioorg Med Chem Lett 19: 360-4 (2009) BindingDB Entry DOI: 10.7270/Q2Q81GDF
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM390773 (US9957263, Example 35) Show SMILES Cn1cc(-c2cc(ccc2Oc2cccc(c2)C(=O)NCCN2CCCC2)S(C)(=O)=O)c2cc[nH]c2c1=O Show InChI InChI=1S/C28H30N4O5S/c1-31-18-24(22-10-11-29-26(22)28(31)34)23-17-21(38(2,35)36)8-9-25(23)37-20-7-5-6-19(16-20)27(33)30-12-15-32-13-3-4-14-32/h5-11,16-18,29H,3-4,12-15H2,1-2H3,(H,30,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...				Bioorg Med Chem Lett 19: 360-4 (2009) BindingDB Entry DOI: 10.7270/Q2Q81GDF
					More data for this Ligand-Target Pair