null

SMILES: CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)C(=O)NCC2(CCOCC2)C(N)=O)c2ccccc12

InChI Key: InChIKey=LCUPOKVAHBTGTA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 392005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 2 of Nuclear receptor ROR-gamma (RORgT) (Homo sapiens (Human))	BDBM392005 (US10301272, Example 6/3) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)C(=O)NCC2(CCOCC2)C(N)=O)c2ccccc12 Show InChI InChI=1S/C32H42N4O5S2/c1-31(2,3)36-43(39,40)26-14-13-24(22-11-7-8-12-23(22)26)27-25(19-21-9-5-4-6-10-21)35-29(42-27)28(37)34-20-32(30(33)38)15-17-41-18-16-32/h7-8,11-14,21,36H,4-6,9-10,15-20H2,1-3H3,(H2,33,38)(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding to RORγ was performed as follows: DNA encodin...				J Med Chem 52: 1814-27 (2009) BindingDB Entry DOI: 10.7270/Q2S184TJ
					More data for this Ligand-Target Pair
Isoform 2 of Nuclear receptor ROR-gamma (RORgT) (Homo sapiens (Human))	BDBM392005 (US10301272, Example 6/3) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)C(=O)NCC2(CCOCC2)C(N)=O)c2ccccc12 Show InChI InChI=1S/C32H42N4O5S2/c1-31(2,3)36-43(39,40)26-14-13-24(22-11-7-8-12-23(22)26)27-25(19-21-9-5-4-6-10-21)35-29(42-27)28(37)34-20-32(30(33)38)15-17-41-18-16-32/h7-8,11-14,21,36H,4-6,9-10,15-20H2,1-3H3,(H2,33,38)(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...				J Med Chem 52: 1814-27 (2009) BindingDB Entry DOI: 10.7270/Q2S184TJ
					More data for this Ligand-Target Pair
Isoform 2 of Nuclear receptor ROR-gamma (RORgT) (Homo sapiens (Human))	BDBM392005 (US10301272, Example 6/3) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)C(=O)NCC2(CCOCC2)C(N)=O)c2ccccc12 Show InChI InChI=1S/C32H42N4O5S2/c1-31(2,3)36-43(39,40)26-14-13-24(22-11-7-8-12-23(22)26)27-25(19-21-9-5-4-6-10-21)35-29(42-27)28(37)34-20-32(30(33)38)15-17-41-18-16-32/h7-8,11-14,21,36H,4-6,9-10,15-20H2,1-3H3,(H2,33,38)(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.16	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells were incubated for additional 16 h before firefly (FF) luciferase activities were measured sequentially in the same cell extract using a Dual-L...				J Med Chem 52: 1814-27 (2009) BindingDB Entry DOI: 10.7270/Q2S184TJ
					More data for this Ligand-Target Pair