BDBM392662 US10301286, Example 88
SMILES: C[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1F)C1CCOCC1)[C@@H](Cc1c(C)cc(C)cc1F)C(O)=O
InChI Key: InChIKey=SDHWYNKMRJOEAU-NWAHNDBCSA-N
Data: 4 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM392662 (US10301286, Example 88) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
GSK | Assay Description Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r... | Bioorg Med Chem Lett 19: 1332-6 (2009) BindingDB Entry DOI: 10.7270/Q2833VCJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Rattus norvegicus) | BDBM392662 (US10301286, Example 88) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
GSK | Assay Description Experiment Method(1) Construction of Rat MC4 Receptor-Expressing VectorA rat MC4 receptor gene (GenBank Accession No.: NM_013099.2) was introduced in... | Bioorg Med Chem Lett 19: 1332-6 (2009) BindingDB Entry DOI: 10.7270/Q2833VCJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 3 (Homo sapiens (Human)) | BDBM392662 (US10301286, Example 88) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 880 | n/a | n/a | n/a | n/a |
GSK | Assay Description Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r... | Bioorg Med Chem Lett 19: 1332-6 (2009) BindingDB Entry DOI: 10.7270/Q2833VCJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocyte-stimulating hormone receptor (Homo sapiens (Human)) | BDBM392662 (US10301286, Example 88) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a |
GSK | Assay Description Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r... | Bioorg Med Chem Lett 19: 1332-6 (2009) BindingDB Entry DOI: 10.7270/Q2833VCJ | |||||||||||
More data for this Ligand-Target Pair |