BDBM392670 US10301286, Example 24

SMILES: CN(C)CC[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)c1ccc(=O)n(C)n1)[C@@H](Cc1ccc2ccccc2c1)C(O)=O

InChI Key: InChIKey=IUFJHLBWWHIENN-WGUPXPKSSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 392670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM392670 (US10301286, Example 24) Show SMILES CN(C)CC[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)c1ccc(=O)n(C)n1)[C@@H](Cc1ccc2ccccc2c1)C(O)=O |r| Show InChI InChI=1S/C37H42F2N6O4/c1-41(2)15-14-28-21-43(33(37(48)49)19-24-8-9-25-6-4-5-7-26(25)18-24)16-17-45(28)36(47)31-23-44(34-12-13-35(46)42(3)40-34)22-30(31)29-11-10-27(38)20-32(29)39/h4-13,18,20,28,30-31,33H,14-17,19,21-23H2,1-3H3,(H,48,49)/t28-,30-,31+,33-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
GSK					Assay Description Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...				Bioorg Med Chem Lett 19: 1332-6 (2009) BindingDB Entry DOI: 10.7270/Q2833VCJ
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM392670 (US10301286, Example 24) Show SMILES CN(C)CC[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)c1ccc(=O)n(C)n1)[C@@H](Cc1ccc2ccccc2c1)C(O)=O |r| Show InChI InChI=1S/C37H42F2N6O4/c1-41(2)15-14-28-21-43(33(37(48)49)19-24-8-9-25-6-4-5-7-26(25)18-24)16-17-45(28)36(47)31-23-44(34-12-13-35(46)42(3)40-34)22-30(31)29-11-10-27(38)20-32(29)39/h4-13,18,20,28,30-31,33H,14-17,19,21-23H2,1-3H3,(H,48,49)/t28-,30-,31+,33-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	580	n/a	n/a	n/a	n/a
GSK					Assay Description Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...				Bioorg Med Chem Lett 19: 1332-6 (2009) BindingDB Entry DOI: 10.7270/Q2833VCJ
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM392670 (US10301286, Example 24) Show SMILES CN(C)CC[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)c1ccc(=O)n(C)n1)[C@@H](Cc1ccc2ccccc2c1)C(O)=O |r| Show InChI InChI=1S/C37H42F2N6O4/c1-41(2)15-14-28-21-43(33(37(48)49)19-24-8-9-25-6-4-5-7-26(25)18-24)16-17-45(28)36(47)31-23-44(34-12-13-35(46)42(3)40-34)22-30(31)29-11-10-27(38)20-32(29)39/h4-13,18,20,28,30-31,33H,14-17,19,21-23H2,1-3H3,(H,48,49)/t28-,30-,31+,33-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a
GSK					Assay Description Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...				Bioorg Med Chem Lett 19: 1332-6 (2009) BindingDB Entry DOI: 10.7270/Q2833VCJ
					More data for this Ligand-Target Pair