BDBM392684 US10301286, Example 72

SMILES: C[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1F)C(C)(C)C)[C@@H](Cc1ccc(OC(F)F)cc1)C(O)=O

InChI Key: InChIKey=PBEQHKYQUKLUOQ-RTDBDVKCSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 392684   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM392684 (US10301286, Example 72) Show SMILES C[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1F)C(C)(C)C)[C@@H](Cc1ccc(OC(F)F)cc1)C(O)=O |r| Show InChI InChI=1S/C30H37ClF3N3O4/c1-18-15-35(26(28(39)40)13-19-5-8-21(9-6-19)41-29(33)34)11-12-37(18)27(38)24-17-36(30(2,3)4)16-23(24)22-10-7-20(31)14-25(22)32/h5-10,14,18,23-24,26,29H,11-13,15-17H2,1-4H3,(H,39,40)/t18-,23-,24+,26-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
GSK					Assay Description Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...				Bioorg Med Chem Lett 19: 1332-6 (2009) BindingDB Entry DOI: 10.7270/Q2833VCJ
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM392684 (US10301286, Example 72) Show SMILES C[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1F)C(C)(C)C)[C@@H](Cc1ccc(OC(F)F)cc1)C(O)=O |r| Show InChI InChI=1S/C30H37ClF3N3O4/c1-18-15-35(26(28(39)40)13-19-5-8-21(9-6-19)41-29(33)34)11-12-37(18)27(38)24-17-36(30(2,3)4)16-23(24)22-10-7-20(31)14-25(22)32/h5-10,14,18,23-24,26,29H,11-13,15-17H2,1-4H3,(H,39,40)/t18-,23-,24+,26-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a
GSK					Assay Description Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...				Bioorg Med Chem Lett 19: 1332-6 (2009) BindingDB Entry DOI: 10.7270/Q2833VCJ
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM392684 (US10301286, Example 72) Show SMILES C[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1F)C(C)(C)C)[C@@H](Cc1ccc(OC(F)F)cc1)C(O)=O |r| Show InChI InChI=1S/C30H37ClF3N3O4/c1-18-15-35(26(28(39)40)13-19-5-8-21(9-6-19)41-29(33)34)11-12-37(18)27(38)24-17-36(30(2,3)4)16-23(24)22-10-7-20(31)14-25(22)32/h5-10,14,18,23-24,26,29H,11-13,15-17H2,1-4H3,(H,39,40)/t18-,23-,24+,26-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
GSK					Assay Description Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...				Bioorg Med Chem Lett 19: 1332-6 (2009) BindingDB Entry DOI: 10.7270/Q2833VCJ
					More data for this Ligand-Target Pair