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SMILES: Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)c(C)n2)s1

InChI Key: InChIKey=IXPINIKYXGHDLU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393246   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 2A


(Homo sapiens (Human))		BDBM393246
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-6...)
Show SMILES Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)c(C)n2)s1
Show InChI InChI=1S/C18H17ClFN5O3S2/c1-10-16(9-24-30(27,28)13-3-4-15(20)14(19)5-13)22-8-17(25-10)18(26)23-7-12-6-21-11(2)29-12/h3-6,8,24H,7,9H2,1-2H3,(H,23,26)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 19.6n/an/an/an/an/an/a



University of Washington at Seattle



Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...

J Med Chem 52: 1864-72 (2009)


BindingDB Entry DOI: 10.7270/Q2KD217B
More data for this
Ligand-Target Pair