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SMILES: Clc1ccccc1CS(=O)(=O)Nc1ccc(cc1)C1=NCC(=O)Nc2c1ccc1ccccc21

InChI Key: InChIKey=RJJRBQMRNAKPMF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393617   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2X purinoceptor 4


(Homo sapiens (Human))		BDBM393617
PNG
(US09969700, 197)
Show SMILES Clc1ccccc1CS(=O)(=O)Nc1ccc(cc1)C1=NCC(=O)Nc2c1ccc1ccccc21 |t:20|
Show InChI InChI=1S/C26H20ClN3O3S/c27-23-8-4-2-6-19(23)16-34(32,33)30-20-12-9-18(10-13-20)25-22-14-11-17-5-1-3-7-21(17)26(22)29-24(31)15-28-25/h1-14,30H,15-16H2,(H,29,31)
KEGG

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n/an/a 440n/an/an/an/an/an/a



Universita del Piemonte Orientale



Assay Description
The P2X4 receptor antagonist activity of the compounds of the present invention was measured as follows. The 1321N1 cells stably expressing human P2X...

J Med Chem 52: 3001-9 (2009)


BindingDB Entry DOI: 10.7270/Q2542QX3
More data for this
Ligand-Target Pair