BDBM393730 US9969726, Example 20

SMILES: O\N=C/c1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1

InChI Key: InChIKey=NGPAQRBYMKYVAK-CFRMEGHHSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 393730   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM393730 (US9969726, Example 20) Show SMILES O\N=C/c1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1 Show InChI InChI=1S/C22H15FN2OS/c23-20-10-9-17(12-19(20)13-24-26)16-7-4-8-18(11-16)21-14-27-22(25-21)15-5-2-1-3-6-15/h1-14,26H/b24-13-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...				J Med Chem 52: 1935-42 (2009) BindingDB Entry DOI: 10.7270/Q2RX9FDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM393730 (US9969726, Example 20) Show SMILES O\N=C/c1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1 Show InChI InChI=1S/C22H15FN2OS/c23-20-10-9-17(12-19(20)13-24-26)16-7-4-8-18(11-16)21-14-27-22(25-21)15-5-2-1-3-6-15/h1-14,26H/b24-13-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...				J Med Chem 52: 1935-42 (2009) BindingDB Entry DOI: 10.7270/Q2RX9FDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM393730 (US9969726, Example 20) Show SMILES O\N=C/c1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1 Show InChI InChI=1S/C22H15FN2OS/c23-20-10-9-17(12-19(20)13-24-26)16-7-4-8-18(11-16)21-14-27-22(25-21)15-5-2-1-3-6-15/h1-14,26H/b24-13-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...				J Med Chem 52: 1935-42 (2009) BindingDB Entry DOI: 10.7270/Q2RX9FDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM393730 (US9969726, Example 20) Show SMILES O\N=C/c1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1 Show InChI InChI=1S/C22H15FN2OS/c23-20-10-9-17(12-19(20)13-24-26)16-7-4-8-18(11-16)21-14-27-22(25-21)15-5-2-1-3-6-15/h1-14,26H/b24-13-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...				J Med Chem 52: 1935-42 (2009) BindingDB Entry DOI: 10.7270/Q2RX9FDX
					More data for this Ligand-Target Pair