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BDBM394105 US9974785, Example 26

SMILES: FC(F)c1cn(c2cc(Cl)cc(N3CCNCC3)c12)S(=O)(=O)c1ccccc1Br

InChI Key: InChIKey=PQNIZUMUQYYWLG-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 394105   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM394105
PNG
(US9974785, Example 26)
Show SMILES FC(F)c1cn(c2cc(Cl)cc(N3CCNCC3)c12)S(=O)(=O)c1ccccc1Br
Show InChI InChI=1S/C19H17BrClF2N3O2S/c20-14-3-1-2-4-17(14)29(27,28)26-11-13(19(22)23)18-15(9-12(21)10-16(18)26)25-7-5-24-6-8-25/h1-4,9-11,19,24H,5-8H2
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US Patent
 1.10n/an/an/an/an/an/an/an/a



Kalypsys Inc.



Assay Description
32 μg membrane proteins of CHO cell expressing human 5-HT6 receptor, 2 nM of radioactive marker [3H]LSD, a compound of the present invention hav...

J Med Chem 52: 3047-62 (2009)


BindingDB Entry DOI: 10.7270/Q27W6FH4
More data for this
Ligand-Target Pair