BDBM394394 N-Methyl-1-[5-(2-methylphenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]methanamine::US10308605, Example 220

SMILES: CNCc1cc(-c2ccccc2C)n(c1)S(=O)(=O)c1cccnc1

InChI Key: InChIKey=SRTTWNYIEACZDL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 394394   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM394394 (N-Methyl-1-[5-(2-methylphenyl)-1-(pyridin-3-ylsulf...) Show SMILES CNCc1cc(-c2ccccc2C)n(c1)S(=O)(=O)c1cccnc1 Show InChI InChI=1S/C18H19N3O2S/c1-14-6-3-4-8-17(14)18-10-15(11-19-2)13-21(18)24(22,23)16-7-5-9-20-12-16/h3-10,12-13,19H,11H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Washington University					Assay Description According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...				J Med Chem 52: 2188-91 (2009) BindingDB Entry DOI: 10.7270/Q2FF3VPK
					More data for this Ligand-Target Pair