null

SMILES: CC(C)(Nc1ncc(cn1)C(=O)c1cccc(c1)C(F)(F)F)c1ccccc1

InChI Key: InChIKey=VPQSHZNXENRMQC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pantetheinase (Homo sapiens (Human))	BDBM395110 (US10308615, Example 121 | {2-[(2- phenylpropan-2- ...) Show SMILES CC(C)(Nc1ncc(cn1)C(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C21H18F3N3O/c1-20(2,16-8-4-3-5-9-16)27-19-25-12-15(13-26-19)18(28)14-7-6-10-17(11-14)21(22,23)24/h3-13H,1-2H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32.3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...				Bioorg Med Chem Lett 19: 3664-8 (2009) BindingDB Entry DOI: 10.7270/Q22809Z8
					More data for this Ligand-Target Pair
Pantetheinase (Homo sapiens (Human))	BDBM395110 (US10308615, Example 121 | {2-[(2- phenylpropan-2- ...) Show SMILES CC(C)(Nc1ncc(cn1)C(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C21H18F3N3O/c1-20(2,16-8-4-3-5-9-16)27-19-25-12-15(13-26-19)18(28)14-7-6-10-17(11-14)21(22,23)24/h3-13H,1-2H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...				Bioorg Med Chem Lett 19: 3664-8 (2009) BindingDB Entry DOI: 10.7270/Q22809Z8
					More data for this Ligand-Target Pair
Pantetheinase (Homo sapiens (Human))	BDBM395110 (US10308615, Example 121 | {2-[(2- phenylpropan-2- ...) Show SMILES CC(C)(Nc1ncc(cn1)C(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C21H18F3N3O/c1-20(2,16-8-4-3-5-9-16)27-19-25-12-15(13-26-19)18(28)14-7-6-10-17(11-14)21(22,23)24/h3-13H,1-2H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50.4	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...				Bioorg Med Chem Lett 19: 3664-8 (2009) BindingDB Entry DOI: 10.7270/Q22809Z8
					More data for this Ligand-Target Pair