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SMILES: Cc1cnn(C)c1-c1ccc(Cc2c(C)nc3nonc3c2N)nc1N

InChI Key: InChIKey=YNSGVWSYYDXEPR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396165   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ghrelin O-acyltransferase


(Homo sapiens (Human))		BDBM396165
PNG
(6-[6-Amino-5-(2,4-dimethyl-2H-pyrazol-3-yl)-pyridi...)
Show SMILES Cc1cnn(C)c1-c1ccc(Cc2c(C)nc3nonc3c2N)nc1N |(6.53,.81,;6.13,-.68,;7.04,-1.93,;6.13,-3.17,;4.67,-2.69,;3.33,-3.47,;4.67,-1.15,;3.33,-.38,;2,-1.15,;.67,-.38,;.67,1.15,;-.67,1.93,;-2,1.15,;-2,-.38,;-.67,-1.15,;-3.33,-1.15,;-4.67,-.38,;-6.13,-.86,;-7.04,.38,;-6.13,1.63,;-4.67,1.15,;-3.33,1.93,;-3.33,3.47,;2,1.93,;3.33,1.15,;4.67,1.93,)|
Show InChI InChI=1S/C17H18N8O/c1-8-7-20-25(3)15(8)11-5-4-10(22-16(11)19)6-12-9(2)21-17-14(13(12)18)23-26-24-17/h4-5,7H,6,18H2,1-3H3,(H2,19,22)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 0.110n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...

Bioorg Med Chem Lett 17: 4664-9 (2007)


BindingDB Entry DOI: 10.7270/Q2VH5R5S
More data for this
Ligand-Target Pair