BDBM396863 US9981950, Example 70

SMILES: CCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(C)c1

InChI Key: InChIKey=HQQFCWPHPRSGTH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 396863   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM396863 (US9981950, Example 70) Show SMILES CCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(C)c1 Show InChI InChI=1S/C15H16ClN5/c1-3-15-17-6-7-20(15)9-12-10-21(19-18-12)13-4-5-14(16)11(2)8-13/h4-8,10H,3,9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.84	n/a	n/a	n/a	n/a	n/a	n/a
Anadys Pharmaceuticals					Assay Description Cells were split 2-3 times weekly between 1:3 and 1:4. For binding assays and membrane preparations the cell culture medium was removed, cells were w...				Bioorg Med Chem Lett 19: 451-8 (2009) BindingDB Entry DOI: 10.7270/Q2TH8Q1D
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM396863 (US9981950, Example 70) Show SMILES CCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(C)c1 Show InChI InChI=1S/C15H16ClN5/c1-3-15-17-6-7-20(15)9-12-10-21(19-18-12)13-4-5-14(16)11(2)8-13/h4-8,10H,3,9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.84	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description TBD				Bioorg Med Chem Lett 18: 3168-72 (2008) BindingDB Entry DOI: 10.7270/Q2JW8H7X
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM396863 (US9981950, Example 70) Show SMILES CCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(C)c1 Show InChI InChI=1S/C15H16ClN5/c1-3-15-17-6-7-20(15)9-12-10-21(19-18-12)13-4-5-14(16)11(2)8-13/h4-8,10H,3,9H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.84	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Male Wistar rats (180 to 200 g) were killed by suffocation in a CO2 chamber for two minutes. Whole brains without cerebellum were removed and dissect...				Bioorg Med Chem Lett 18: 3168-72 (2008) BindingDB Entry DOI: 10.7270/Q2JW8H7X
					More data for this Ligand-Target Pair