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SMILES: CCc1nccn1Cc1cn(nn1)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=ZUBNWKBIEHKLQD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 396865   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM396865 (US9981950, Example 72) Show SMILES CCc1nccn1Cc1cn(nn1)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C15H14F3N5O/c1-2-14-19-6-7-22(14)9-11-10-23(21-20-11)12-4-3-5-13(8-12)24-15(16,17)18/h3-8,10H,2,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.4	n/a	n/a	n/a	n/a	n/a	n/a
Anadys Pharmaceuticals					Assay Description Cells were split 2-3 times weekly between 1:3 and 1:4. For binding assays and membrane preparations the cell culture medium was removed, cells were w...				Bioorg Med Chem Lett 19: 451-8 (2009) BindingDB Entry DOI: 10.7270/Q2TH8Q1D
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM396865 (US9981950, Example 72) Show SMILES CCc1nccn1Cc1cn(nn1)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C15H14F3N5O/c1-2-14-19-6-7-22(14)9-11-10-23(21-20-11)12-4-3-5-13(8-12)24-15(16,17)18/h3-8,10H,2,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description TBD				Bioorg Med Chem Lett 18: 3168-72 (2008) BindingDB Entry DOI: 10.7270/Q2JW8H7X
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM396865 (US9981950, Example 72) Show SMILES CCc1nccn1Cc1cn(nn1)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C15H14F3N5O/c1-2-14-19-6-7-22(14)9-11-10-23(21-20-11)12-4-3-5-13(8-12)24-15(16,17)18/h3-8,10H,2,9H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Male Wistar rats (180 to 200 g) were killed by suffocation in a CO2 chamber for two minutes. Whole brains without cerebellum were removed and dissect...				Bioorg Med Chem Lett 18: 3168-72 (2008) BindingDB Entry DOI: 10.7270/Q2JW8H7X
					More data for this Ligand-Target Pair