BDBM3991 1 H-indole-3-alkanamide deriv. 10b::2-(2-{[3-(cyanomethyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)acetonitrile

SMILES: N#CCc1c(SSc2[nH]c3ccccc3c2CC#N)[nH]c2ccccc12

InChI Key: InChIKey=WRQVNXDOWPRYHH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3991   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase transforming protein Src (Avian sarcoma virus)	BDBM3991 (1 H-indole-3-alkanamide deriv. 10b | 2-(2-{[3-(cya...) Show SMILES N#CCc1c(SSc2[nH]c3ccccc3c2CC#N)[nH]c2ccccc12 Show InChI InChI=1S/C20H14N4S2/c21-11-9-15-13-5-1-3-7-17(13)23-19(15)25-26-20-16(10-12-22)14-6-2-4-8-18(14)24-20/h1-8,23-24H,9-10H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 37: 598-609 (1994) Article DOI: 10.1021/jm00031a009 BindingDB Entry DOI: 10.7270/Q2MS3QZH
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3991 (1 H-indole-3-alkanamide deriv. 10b | 2-(2-{[3-(cya...) Show SMILES N#CCc1c(SSc2[nH]c3ccccc3c2CC#N)[nH]c2ccccc12 Show InChI InChI=1S/C20H14N4S2/c21-11-9-15-13-5-1-3-7-17(13)23-19(15)25-26-20-16(10-12-22)14-6-2-4-8-18(14)24-20/h1-8,23-24H,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	7.4	22
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 37: 598-609 (1994) Article DOI: 10.1021/jm00031a009 BindingDB Entry DOI: 10.7270/Q2MS3QZH
					More data for this Ligand-Target Pair