BDBM3996 1 H-indole-3-alkanamide deriv. 10e::2,2 -Dithiobis(1H-indole-3-propanamide)::3-(2-{[3-(2-carbamoylethyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)propanamide

SMILES: NC(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(N)=O)[nH]c2ccccc12

InChI Key: InChIKey=HMHMZJJRNBZGQN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3996   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase transforming protein Src (Avian sarcoma virus)	BDBM3996 (1 H-indole-3-alkanamide deriv. 10e | 2,2 -Dithiobi...) Show SMILES NC(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(N)=O)[nH]c2ccccc12 Show InChI InChI=1S/C22H22N4O2S2/c23-19(27)11-9-15-13-5-1-3-7-17(13)25-21(15)29-30-22-16(10-12-20(24)28)14-6-2-4-8-18(14)26-22/h1-8,25-26H,9-12H2,(H2,23,27)(H2,24,28)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 37: 598-609 (1994) Article DOI: 10.1021/jm00031a009 BindingDB Entry DOI: 10.7270/Q2MS3QZH
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3996 (1 H-indole-3-alkanamide deriv. 10e | 2,2 -Dithiobi...) Show SMILES NC(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(N)=O)[nH]c2ccccc12 Show InChI InChI=1S/C22H22N4O2S2/c23-19(27)11-9-15-13-5-1-3-7-17(13)25-21(15)29-30-22-16(10-12-20(24)28)14-6-2-4-8-18(14)26-22/h1-8,25-26H,9-12H2,(H2,23,27)(H2,24,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	7.4	22
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 37: 598-609 (1994) Article DOI: 10.1021/jm00031a009 BindingDB Entry DOI: 10.7270/Q2MS3QZH
					More data for this Ligand-Target Pair