BDBM400242 N-(6-(1H-Imidazol-1-yl)pyridin-3-yl)-3-(cyclopropylmethyl)-7-methyl-3H-imidazo[4,5-b]pyridin-5-amine::US10016439, 158
SMILES: Cc1cc(Nc2ccc(nc2)-n2ccnc2)nc2n(CC3CC3)cnc12
InChI Key: InChIKey=NBMBJGUURXSJBY-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM400242 (N-(6-(1H-Imidazol-1-yl)pyridin-3-yl)-3-(cyclopropy...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-5 (Homo sapiens (Human)) | BDBM400242 (N-(6-(1H-Imidazol-1-yl)pyridin-3-yl)-3-(cyclopropy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 18.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd US Patent | Assay Description The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ... | US Patent US10016439 (2018) BindingDB Entry DOI: 10.7270/Q2NC63J0 | |||||||||||
More data for this Ligand-Target Pair |