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SMILES: Cc1cc2ccccc2nc1-c1cn(nn1)-c1ccc(O)cc1

InChI Key: InChIKey=ZZBLRMHMEXARSY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403755   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM403755 (US10336721, Example 11 | US10968198, Example 11) Show SMILES Cc1cc2ccccc2nc1-c1cn(nn1)-c1ccc(O)cc1 Show InChI InChI=1S/C18H14N4O/c1-12-10-13-4-2-3-5-16(13)19-18(12)17-11-22(21-20-17)14-6-8-15(23)9-7-14/h2-11,23H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University US Patent					Assay Description Data obtained for the Example compounds, obtained using the methods described in Example B.				US Patent US10968198 (2021)
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM403755 (US10336721, Example 11 | US10968198, Example 11) Show SMILES Cc1cc2ccccc2nc1-c1cn(nn1)-c1ccc(O)cc1 Show InChI InChI=1S/C18H14N4O/c1-12-10-13-4-2-3-5-16(13)19-18(12)17-11-22(21-20-17)14-6-8-15(23)9-7-14/h2-11,23H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Inhibition of the tautomerase activity of MIF was measured using 4-hydroxyphenyl pyruvic acid (HPP) as substrate, largely following previously report...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2RR1WNP
					More data for this Ligand-Target Pair